3. The development of technology for the manufacture of x-ray sources on the basis
of radionuclides iodine-125 and tellurium-125m for brachytherapy.

The technology for the manufacture of two kinds of x-ray sources for brachytherapy (a technique for performing radiation therapy in which the radiation source, or seed, is placed inside the tumor to kill the malignant cell from within) was developed. The first represented a titanium capsule (0.8 mm in outside diameter and 4 mm in length), charged with iodine-125 on a carrier and sealed with laser welding. In the source of the second kind a titanium capsule was charged with the stable isotope Te-124 enriched above 90% as metal or dioxide. Activation of the source with thermal neutrons was performed after the assembling of the source. The radionuclides I-125 and Te-125m have similar nuclear physical characteristics of decay. However the technology of manufacture for the sources on a basis of radionuclide Te-125m was simpler and it involved the less number of radiationally dangerous stages.

The experimental samples of the x-ray sources were manufactured. The source on the basis of radionuclide Te-125m did not have foreign analogues.

Historical overview of main activities