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The European Physical Journal B
ISSN: 1434-6028 (printed version)
ISSN: 1434-6036 (electronic version)
Abstract Volume 3 Issue 2 (1998) pp 271-276
The effect of DNA phase structure on DNA walks
S. Cebrat (1) (a), M.R. Dudek (2) (b)
(1) Institute of Microbiology, University of Wroclaw, ul. Przybyszewskiego 63/77, 51-148 Wroclaw, Poland
(2) Institute of Theoretical Physics, University of Wroclaw, pl. Borna 9, 50-204 Wroclaw, Poland
Received: 8 January 1998 / Received in final form and Accepted: 28 January 1998
Abstract: We have performed several kinds of DNA walks which often are the first steps for further analysis of DNA structure and long range correlations. The DNA walks analysing frequency of G+C versus A+T cannot indicate the coding strand while purine versus pyrimidine DNA walks or two-dimensional (A-T,G-C) DNA walks in some instances can indicate the coding strand but cannot resolve the coding frame. The modified two-dimensional (A-T,G-C) DNA walks respecting the three-nucleotide codon structure show very high correlation in nucleotide composition of DNA coding sequences. They can distinguish between coding and non-coding sequences and indicate the strand and the phase in which DNA is coding.
PACS. 02.50.Fz Stochastic analysis - 42.62.Be Biological and medical applications - 02.70.Rw Other computational methods
(a) email: cebrat@angband.microb.uni.wroc.pl
(b) email: mdudek@ift.uni.wroc.pl
Article in PDF-Format (1048 KB)
Online publication: July 9, 1998
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